Curation Information

Publication

Bacillus subtilis Fur represses one of two paralogous haem-degrading monooxygenases.;Gaballa A, Helmann JD;Microbiology (Reading, England) 2011 Nov; 157(Pt 11):3221-31 [21873409]

TF

Fur [P54574, view regulon]

Reported TF sp.

Bacillus subtilis subsp. subtilis str. 168

Reported site sp.

Bacillus subtilis subsp. subtilis str. 168

Created by

Dinara Sagitova

Curation notes

-

Experimental Process

Fur-mediated regulation of the hmoA gene was validated by constructing hmoA–cat–lacZ fusion. EMSA showed that Fur bound with high affinity to the hmoA regulatory region.

Transcription Factor Binding Sites

• Sites reported in the paper
• Sites matched in the genome

Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.