Curation Information

Publication
Characterization of relA and codY mutants of Listeria monocytogenes: identification of the CodY regulon and its role in virulence.;Bennett HJ, Pearce DM, Glenn S, Taylor CM, Kuhn M, Sonenshein AL, Andrew PW, Roberts IS;Molecular microbiology 2007 Mar; 63(5):1453-67 [17302820]
TF
CodY [Q8Y7J7, view regulon]
Reported TF sp.
Listeria monocytogenes EGD-e
Reported site sp.
Listeria monocytogenes EGD-e
Created by
Kevin Nguyen
Curation notes
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Experimental Process

Microarray analyses was used to identify CodY regulon. Gel shift assay demonstrated binding of CodY to the promoter. The binding site was then mapped using DNase footprinting.

Transcription Factor Binding Sites


TTTTTGTATATTATATACATAATAAATAACTTAAAATGCATAAAATAGTT
TTTTTGTATATTATATACATAATAAATAACTTAAAATGCATAAAATAGTT

Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type