Curation Information

Publication
DNA recognition by beta-sheets in the Arc repressor-operator crystal structure.;Raumann BE, Rould MA, Pabo CO, Sauer RT;Nature 1994 Feb 24; 367(6465):754-7 [8107872]
TF
Arc [A8CG91, view regulon]
Reported TF sp.
Enterobacteria phage P22
Reported site sp.
Enterobacteria phage P22
Created by
Erill Lab
Curation notes
-
External databases
Protein Data Bank (1PAR) .

Experimental Process

Arc tetramer was co-crystallized in complex with the arc operator sequence and examined at 2.6 Å resolution

Transcription Factor Binding Sites


ATAGTAGAGTGCTTCTATCAT
ATAGTAGAGTGCTTCTATCAT

Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type
ATAGTAGAGTGCTTCTATCAT
... ... mnt orf59a ant arc
Experimental technique details X-ray crystallography (ECO:0005670) - repressor tetramer